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Menopause: changes, choice and HRT
Publisher
Rockpool Publishing
Publication Date
2013
Language
English
Description
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Table of Contents
From the Book
How to use this book
Author's Note
Prologue
Introduction
Section 1. History, Menopause, HHT and the Women's Health Initiative Study
1. A History of the Menopause and HRT
A history of management of the menopause
Sex and its influence on the undemanding of menopause
The development of effective hormone therapy
The development of oral contraception and HRT
The development of Hormone Replacement Therapy (HRT)
Summary
2. The Anatomy and Physiology of the Menopause
Menopause
Peri-menopause
Post-menopause
Premature menopause
The endocrine system
Ovarian hormones
Anatomy of the reproductive organs of the pelvis
Ovarian physiology and the sex hormones
The end of female production of estradiol and progesterone
Physiological changes during peri-menopause
Summary
3. The Women's Health Initiative Study
The Study
The suitability of women selected for HRT studies
Unfortunate consequences of the WHI Study
Medical research reports, studies and their interpretation
Summary
Section 2. Menopause and Health
4. Hormones and Genital Cancer
Endometrial (uterine) cancer
Ovarian cancer
Breast cancer
Genetic mutations in pre-menopausal women
Risk factors associated with development of breast cancer
Cluster cancers
Summary
5. Estrogen and the Cardiovascular System
The protective effect of estrogen
Thrombosis (clot)
Varicose veins
Summary
6. Osteopaenia and Osteoporosis
Bone mineral density studies
The role of estrogen in prevention and treatment of osteoporosis
The increased risk of osteoporosis for a woman who stops HRT
Summary
7. Hormones, Brain Function, Memory and Dementia
Alzheimer's dementia
Summary
8. Loss of Libido (Hypoactive Sexual Desire Disorder)
Estrogen, progesterone and testosterone
Summary
Section 3. Management of Menopause
9. Hormone Replacement Therapy Regimens
The development of hormone therapy regimens
Progesterone and progestogens (progestins)
Testosterone
Prescribing advice and HRT
For how long should HRT be used?
Summary
10. Methods of Delivering HRT Regimens
Oral hormone therapy regimens
Transdermal therapy regimens
Hormone implants
Troches
Vaginal therapy
Summary
11. Adverse Side-Effects of HRT
Breakthrough bleeding
Mastalgia
Skin, hair growth and hair loss
Weight gain
Summary
12. Other Medical Treatments for Menopause
(SERMs) Specific estrogen receptor modulators
Neurotransmitter modulators
Summary
13. Complementary and Alternative Therapies for the Menopause
Proof of efficacy
Vitamins
Soy products
Red clover extract (Promensil)
Black cohosh (Remifemin)
Evening primrose oil
Traditional Chinese herbal medicines-Ginseng and Dong Quai
Progesterone cream
Wild yam cream
DHEAS (Dehydroepiandrosterone sulphate)
Over-the-counter products
Summary
14. HRT Following Breast Cancer, Endometriosis or Fibroids
HRT after breast cancer
HRT and endometriosis
HRT and fibroids (fibromyoma)
Summary
Section 4. Choices
15. The Balance and Beauty of Ageing
16. Menopause Today
Epilogue
Section 5.
Glossary
Acronyms
Appendices
Appendix 1. Therapeutic goods administration (TGA)
Appendix 2. Oral hormone preparations: estrogen/progesterone progestogens
Appendix 3. Progestogens for use with estrogens
Appendix 4. Transdermal therapy regimens - patches, creams, gels, sprays
Appendix 5. (SERMs)
Appendix 6. Neurotransmitter modulators used for menopause symptoms
Appendix 7. Treatments of osteopaenia and osteoporosis
Appendix 8. Hormones involved in homeostasis (balance) in humans
Appendix 9. Hormones and cancer
Appendix 10. Assessing research in medical studies
Endnotes
Acknowledgments
Index
About the Authors
Excerpt
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Author Notes
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More Details
ISBN
9781921878695
192187869
192187869
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